SLU-PP-332 | 10 vials

SLU-PP-332 is a novel synthetic compound classified as a pan-Estrogen-Related Receptor (ERR) agonist that functions as an exercise mimetic . Developed by researchers at Washington University and Saint Louis University, it activates all three forms of estrogen-related receptors (ERRα, ERRβ, and ERRγ)—specialized proteins that are normally triggered by physical exercise .

Key Specifications:

• CAS Number: 303760-60-3

• Molecular Formula: C₁₈H₁₄N₂O₂

• Molecular Weight: 290.3 g/mol

• Purity: ≥98-99% (research grade)

• Appearance: White to off-white solid/powder

• Solubility: Soluble in DMSO

• Storage: Store at -20°C

Mechanism of Action: SLU-PP-332 acts as a potent pan-ERR agonist with the following binding affinities :

• ERRα: EC₅₀ = 98 nM

• ERRβ: EC₅₀ = 230 nM

• ERRγ: EC₅₀ = 430 nM

By activating these nuclear receptors, it :

• Enhances mitochondrial function and cellular respiration

• Increases energy expenditure and fatty acid oxidation

• Promotes oxidative muscle fibers (Type IIa)

• Improves exercise endurance

Research Applications:

Cognitive & Neuroprotective Potential:

Emerging research suggests SLU-PP-332 may have significant applications in neurodegenerative conditions :

• Appears to counter damaging processes that occur in the brains of Alzheimer's patients

• Shows potential benefits against cognitive decline with age

• May protect against other neurodegenerative conditions

• Mitochondrial enhancement in brain cells could support cognitive function

Important Notice: FOR RESEARCH USE ONLY. NOT FOR HUMAN USE, THERAPEUTIC, OR DIAGNOSTIC APPLICATIONS.