Semaglutide is a 31-amino acid synthetic peptide and glucagon-like peptide-1 (GLP-1) receptor agonist developed for metabolic research . It mimics the action of the natural gut hormone GLP-1, regulating insulin secretion, appetite, and energy balance .
Key Specifications:
CAS Number: 910463-68-2
Molecular Formula: C₁₈₇H₂₉₁N₄₅O₅₉
Molecular Weight: 4114 g/mol
Sequence Length: 31 amino acids
Purity: ≥99%
Half-life: Approximately 7 days (supports once-weekly administration)
Mechanism of Action: Semaglutide activates GLP-1 receptors, leading to:
Glucose-dependent insulin secretion
Reduced glucagon release
Slowed gastric emptying
Increased satiety and reduced appetite
Research Applications:
Type 2 diabetes and glycemic control
Obesity and weight management studies
Cardiovascular research (MACE reduction)
Metabolic-associated steatohepatitis (MASH)
Chronic kidney disease
Heart failure with preserved ejection fraction
Obstructive sleep apnea
Neuroprotection and Alzheimer's disease
Research Use Only. Not for human consumption.
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