CJC-1295 no DAC | 10 vials
CJC-1295 (No DAC) is a synthetic peptide analog of growth hormone-releasing hormone (GHRH), specifically a modified fragment of GHRH(1-29) . Unlike the DAC-conjugated version, this formulation does not contain a Drug Affinity Complex (DAC) moiety, resulting in a significantly shorter half-life in circulation .
Key Specifications:
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CAS Number: 446036-97-1 (some sources list 863288-34-0)
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Synonyms: Modified GRF (1-29), CJC-1295-no DAC, GHRH (1-29)-NH2, GRF 1-29
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Molecular Formula: C₁₅₂H₂₅₂N₄₄O₄₂
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Molecular Weight: 3367.9 Da
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Purity: ≥98% (research grade)
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Appearance: White lyophilized powder
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Storage: Store at -20°C; protect from light and moisture
Mechanism of Action:
CJC-1295 binds to GHRH receptors in the anterior pituitary gland, stimulating the secretion of growth hormone (GH) . Key features include:
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Resists enzymatic degradation compared to endogenous GHRH, prolonging its activity
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Increases GH secretion in primary rat anterior pituitary cells at picomolar to micromolar concentrations
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Stimulates pulsatile GH release, mimicking natural GH secretion patterns
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Elevates IGF-1 levels downstream of GH stimulation
Key Research Applications:
| Category | Applications |
|---|---|
| Growth Hormone Research | GH pulse amplitude, somatotroph function, IGF-1 axis studies |
| Muscle & Metabolism | Protein synthesis, lean mass, lipolysis, metabolic regulation |
| Anti-Aging Research | Age-related GH decline, body composition, tissue regeneration |
| Tissue Repair | Collagen synthesis, connective tissue healing, recovery models |
| Cognitive Research | Emerging studies on GH/IGF-1 and neuroprotection, synaptogenesis |
Important Notice:
FOR RESEARCH USE ONLY. NOT FOR HUMAN USE, THERAPEUTIC, OR DIAGNOSTIC APPLICATIONS.
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Key Benefits
- High purity research compound (>98%)
- Third-party tested and verified
- Lyophilized for maximum stability
- Certificate of analysis available
